In the preoperative period, with lung cancer cases of lung cancer, it is possible not only to determine the functional reserves of respiration and blood circulation, but also to establish the connection between the revealed disorders and the prevalence of the oncological process. Table 10 presents the sample data of the functional study of two groups of patients with lung cancer, who were subsequently performed advanced (group 1, n = 268) and advanced combined pneumonectomy (group 2, n = 176). Patients in both groups were comparable in age, nature of the disorders associated with the main and associated diseases.
The initial condition of patients in the first group was characterized by maintaining a practically normal value of one-time cardiac performance (the mathematically expected UI value for this group is 46.4 ± 8.6 ml – ), lack of tachycardia, normal systemic arterial tone, poorly expressed general exsicosis, adequate, close to due IOC values. At the same time, it should be noted the presence of hemodynamic manifestations of respiratory failure, expressed in an increase in the value of the coefficient of respiratory changes in the stroke volume of the left ventricle to 1.4 ± 0.12, in the absence of tachypnoe at rest. Marked respiratory failure can be classified as moderate and fully compensated for hemodynamically, which was characterized by an increase in the value of the circulatory reserve ratio to 1.12 ± 0.11.
In the second group of patients who subsequently underwent expanded combined pneumonectomy, the preoperative functional status of the cardiovascular and respiratory systems was somewhat different from the previous group of patients.
First, a slight decrease in one-time cardiac performance was noted. UA was 36.8 ± 3.2 ml . m – , with a mean value of 47.3 ± 8.7 ml . m – . However, the observed moderate tachycardia (HR = 83.1 ± . 3.7 beats . Min – ) provide substantially equal to the previous group of volume flow mode (SI = 3.0 ± 0.12 l . M – . M – ; SF = 1 , 10 ± 0.14).
Secondly, in this group of patients were not only saved, but also more pronounced hemodynamic manifestations of respiratory failure (CDI = 1.44 ± 0.17), however, hemodynamic compensation was maintained (CI = 1.10 ± 0.14).
In general, both groups of patients were in the same qualitative characteristics of the functional status. The second group seems to be more compromised in comparison with the first, but the size of the sigmal interval does not reveal significant differences. In principle, one can note the good preservation of one-time cardiac performance, moderate hemodynamic manifestations of respiratory failure, and compensated development of a moderate hyperdynamic circulation regime.
When studying the functional state of patients, it is necessary to take into account the presence or absence of inflammatory paracancrosis changes in the lung and surrounding tissues. Paracancic infection has an adverse effect on all stages of treatment of patients with lung cancer in the surgical clinic: in the preoperative period, during surgery and during postoperative therapy. The timely diagnosis and treatment of paracancrosis inflammatory changes largely determines the success of patient treatment. In addition, in this situation, the operation performs a sanifying function, improving the general condition of the patient.