Combined and complex surgical treatment of patients with lung cancer in advanced stages of the disease is traditionally based on the use of radiation and chemotherapy. The many years that have passed since the beginning of the formation of radiation and chemotherapeutic methods of treating cancer patients, the methods of their combined effect, aimed at improving the efficiency of surgical removal of the tumor and its regional metastases, continue to improve and deepen. This is connected both with the expansion of knowledge about the biology of malignant tumors, and with the creation and use of powerful X-ray therapy facilities, gammatrons, betatrons and linear accelerators, as well as with the discovery and synthesis of new groups of antitumor drugs.

The use of auxiliary (additional) methods of antitumor effects (for example, immunotherapy) in complex surgical treatment of lung cancer has not yet led to noticeable results and is more promising than real, although there are encouraging reports about the effectiveness of their use and there is every reason to assume that In the future, they may substantially complement or even compete with traditional methods of treating cancer patients.