Dynamics of morphological and functional indicators

The dynamics of morphological and functional parameters of platelet hemostasis in the same groups of patients are presented in table 23. From the data presented it can be seen that the studied parameters clearly differed from the normal ones. Baseline platelet abnormalities were characterized by a tendency to thrombocytosis, an increase in the acid phosphatase content and a decrease in the glycogen content in the cells, as well as their tendency to slow down and poorly reversible aggregation.

The features of changes in the functional properties of platelets at various times after surgery with a complicated and favorable course of the postoperative period are reflected. Operating trauma and blood loss, despite its adequate replenishment, led to a noticeable decrease in the number of circulating platelets and exacerbate the existing platelet disorders in the first three days in all patients, regardless of the features of the postoperative course. In patients with complications, the deterioration of the morphological and functional parameters of platelet hemostasis was more profound. In the future, these changes became multidirectional. If patients have a favorable background The postoperative course at the subsequent stages of the study showed a clear tendency to normalize all the cytochemical and functional parameters studied by us, in cases of occurrence of postoperative thrombosis and purulent infectious complications until their resolution, the described violations continued to aggravate.

Conducted clinical and laboratory parallels allowed to establish that the most significant platelet and erythrocyte disorders were patients with severe respiratory failure, especially when they developed in patients with massive operative blood loss, which required the use of significant erythrocyte containing homologous transfusion media.

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